A red-emitting water-soluble fluorescent probe for biothiol detection with a large Stokes shift |
| |
| Authors: | Lei Yang Haiqing Xiong Yuanan Su Huihui Tian Xingjiang Liu Xiangzhi Song |
| |
| Affiliation: | College of Chemistry & Chemical Engineering, Central South University Changsha 410083, China; Key Laboratory of Hunan Province for Water Environment and Agriculture Product Safety, Changsha 410083, China; College of Chemistry & Molecular Engineering, Zhengzhou University, Zhengzhou 450001, China |
| |
| Abstract: | In this work, we presented a fluorescent probe (MCQ-DNBS) for selective and sensitive detection of biothiols based on a methylated chromenoquinoline (MCQ) derivative. Probe MCQ-DNBS was constructed by masking the OH group in MCQ with a common sensing unit, 2,4-dinitrobezensulfonate group (DNBS) for biothiols. Due to the photo-induced electron transfer (PET) process between MCQ and DNBS, this probe was weekly fluorescent. Upon the addition of biothiols (Cys, Hcy and GSH), this probe emitted a strong red fluorescence (λlem max=613 nm) with a large Stokes shift (115 nm). In addition, fluorescence imaging of biothiols in living cells was successfully realized using MCQ-DNBS as a detector. |
| |
| Keywords: | Fluorescent probe Biothiol Water-soluble Red-emitting Large Stokes shift |
| 本文献已被 维普 ScienceDirect 等数据库收录！ |
| 点击此处可从《中国化学快报》浏览原始摘要信息 |
|
点击此处可从《中国化学快报》下载全文 |
|
