Synthesis of imidazo[1,2-a]pyridine-6-carbohydrazides and 1H-pyrido[1,2-a]pyrimidine-7-carbohydrazides |
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Authors: | Mohammad Bayat Fahimeh Sadat Hosseini |
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Affiliation: | Chemistry Department, Imam Khomeini International University, Qazvin, Iran |
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Abstract: | The one-pot, multicomponent synthesis of imidazopyridine and pyridopyrimidine fused heterocyclic systems from readily available diamines, l,l-bis(methylthio)-2-nitroethene, cyanoacetohydrazide and aromatic aldehydes in good to high yields is described. This protocol has the advantages of simple work-up, mild reaction conditions, absence of catalyst and provides an entry point to fused heterocyclic structures. |
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Keywords: | Fused pyrimidine 1,1-Bis(methylthio)-2-nitroethene Cyanoacetohydrazide Aromatic aldehyde Multi-component reaction |
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