Synthesis and hydrolytic degradation of stereoregular aromatic poly(ester amide)s derived from D‐xylose |
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Authors: | Inmaculada Molina Pinilla Manuel Bueno Martínez Juan A Galbis |
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Institution: | Departamento de Química Orgánica y Farmacéutica, Facultad de Farmacia, Universidad de Sevilla, 41012‐Sevilla, Spain |
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Abstract: | Stereoregular poly(ester amide)s (PEAs) were prepared by the polycondensation method using naturally occurring D ‐xylose and aromatic diacids as the starting materials. The polymers were characterized by elemental analysis, GPC, IR, and 1H‐ and 13C NMR spectroscopies. Thermal and X‐ray diffraction studies revealed them to be mainly amorphous. The polymers are hydrophilic and their degradation studies were carried out at 37 and 80 °C in buffered salt solution at pH 8. The degradation study was monitored by mass loss, GPC, IR, and NMR spectroscopies. The hydrolytic degradation of these PEAs occurred rapidly by hydrolysis of the ester functions to a final compound, which maintained the amide functions. © 2010 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2010 |
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Keywords: | carbohydrate‐based polymers chiral degradation hydrophilic polymers stereoregular poly(ester amide)s |
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