SPECTROMETRIE DE MASSE DES AMINO-4 STEROIDES

The mass spectrometric fragmentation of the 4-amino steroids has been studied and interpretations are proposed for the formation of the principal fragments. The loss of a primary radical in the principal fragmentations explains the low rate constant of these reactions, as shown by the occurrence of important intramolecular H-D scrambling in the case of the deuterated derivative in positions 3 and 5.