Influence of temperature on neuronal excitability in cochlear nucleus |
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Authors: | Ting Zeng Jiafu Wang and Shenbing Kuang |
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Institution: | (1) Department of Physiology, Neuroscience Training Program, University of Wisconsin-Madison, Madison, WI, USA; |
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Abstract: | The influence of temperature on neuronal excitability is studied by numerical simulations on the spiking threshold characteristics
of bushy cells in cochlear nucleus periodically stimulated by synaptic currents. The results reveal that there is a cut-off
frequency for the spiking of bushy cell in a specific temperature environment, corresponding to the existence of a critical
temperature for the neuron to respond with real spikes to the synaptic stimulus of a given frequency, due to the finiteness
of spike width. An optimal temperature range for neuronal spiking is also found for a specific stimulus frequency, and the
temperature range span decreases with increasing stimulus frequency. These findings imply that there is a physiological temperature
range which is beneficial for the information processing in auditory system. |
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Keywords: | |
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