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Synthesis of hydroxybenzaldehyde derivatives containing an isoxazole heteroring |
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| Authors: | Potkin V. I. Gadzhily R. A. Dikusar E. A. Petkevich S. K. Zhukovskaya N. A. Aliev A. G. Nagieva Sh. F. |
| Affiliation: | 1.Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus, ul. Surganova 13, Minsk, 220072, Belarus ;2.Institute of Polymeric Materials, National Academy of Sciences of Azerbaijan, Sumgait, Azerbaijan ; |
| Abstract: | 5-Phenyl(p-tolyl)isoxazole-3-carboxylic acids were synthesized starting from 3-hydroxyiminomethyl-5-phenyl(p-tolyl)isoxazoles, and their reactions with p-hydroxybenzaldehyde, vanillin, isovanillin, o-vanillin, and ethyl vanillin gave the corresponding esters. The latter were brought into condensation with aromatic amines to obtain Schiff bases which were reduced to amines. |
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