| Abstract: | Photopromoted carbonylation of 1-bromo-6-chlorohexane with CO catalyzed by CuBr2 and CdI2 has been carried out underambient conditions. The results indicate that the carbonylation proceeds with the major product of chlorocsterCICH2(CH2)<,5COOCH3 under catalysis of CuBr2. Furthermore, the activity of the carbonylation can be improved by additionof basic additives (NaOAc, Na3PO<,4 or (n-C<4,H<,9)3N). Among these additives, (n-C<4,H<,9)3N is the most efficient in terms of the yield ofClCH2(CH2)<,5COOCH3. However, the methoxycarbonyl substituting chlorine product of BrCH2(CH2)<,5COOCH3 is not obtained inthe presence of CdI2. This is quite different from the carbonylation of monochloroalkane.2008 Jing Mei Yin. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved. |
