Mollification of Cytotoxicity of Sulfated Polysaccharides by Fibroblast Growth Factors1 |
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Authors: | Megumi Kunou Takashi Ohtsuki Toshihiro Akaike Kenichi Hatanaka |
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Institution: | Department of Biomolecular Engineering , Tokyo Institute of Technology , Nagatsuta, Midori-ku, Yokohama, 227, Japan |
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Abstract: | Abstract Sulfated polysaccharide which had a relatively high degree of sulfation showed cytotoxicity to 3T3-L1 fibroblasts. Acidic and basic fibroblast growth factors inhibited the cell damage caused by the sulfated polysaccharides, while epidermal growth factor and platelet growth factor had no effects. |
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