Synthesis of Ether-Linked Di- and Trisaccharide Derivatives Part II- Functionalization and Potential Applications of Ether-Linked Di- and Trisaccharides Containing d-Glucose |
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Authors: | Pierre Y Gouéth Mamy Fauvin Isabelle Chellé-Regnaut Gino Ronco Pierre Villa |
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Institution: | Laboratoire de Chimie Organique et Cinétique , U.F.R des Sciences Fondamentales et Exactes, Université de Picardie , 33, rue Saint Leu, 80000 , Amiens , France |
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Abstract: | Abstract We have prepared three series of functionalized disaccharides of the type A(6→n)B and a trisaccharide with the formula A-O-B-O-C, in which A = D-glucose (or its derivatives) and both B and C are any of D-fructose, D-galactose, D-glucose, xylitol and glycerol (or their derivatives). These compounds resulted from the regiospecific functionalization of either A or B and either the partial or total deprotection of either 6-O-(3-deoxy-1,2:5,6-di-O-isopropylidene-α-D-glucofuranos-3-yl)-3-O-alkyl-1,2-O-isopropylidene-α-D-glucofuranose or its analogues of type 1 described in part I.1 We also report results on surface activity and biological properties of some of the molecules prepared. |
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