| 青蒿素与辅酶A作用的研究 |
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| 引用本文： | 娄凤文.青蒿素与辅酶A作用的研究[J].淮阴师范学院学报(自然科学版),2005,4(2):131-135. |
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| 作者姓名： | 娄凤文 |
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| 作者单位： | 淮阴师范学院,化学系,江苏,淮安,223300 |
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| 摘 要： | 首次提出了青蒿素分子以疟原虫体内的生物活性物质辅酶A分子作为靶标的抗疟机制的新模型,并从生化原理和实验上对青蒿素类药通过辅酶A对疟原虫的致死作用给出了合理的解释,获得了预期的结果.
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| 关 键 词： | 青蒿素 辅酶A 抗疟机制 |
| 文章编号： | 1671-6876(2005)02-0131-05 |
| 修稿时间： | 2004年9月19日 |
Research on the Effects of Artemisinin and Coenzyme A |
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| LOU Fen-weng.Research on the Effects of Artemisinin and Coenzyme A[J].Journal of Huaiyin Teachers College(Natrual Science Edition),2005,4(2):131-135. |
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| Authors: | LOU Fen-weng |
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| Abstract: | For the first time, presents a neas antimalarial me chanism mode that the artemisinin molecules target on coenzumeA,an active subsrtance existing in plasmodia; Besides,the author.reasonably sxplains ard explores, in accordance with the biochemical theories and his experiments, the lethal effects of artemisinin through coenzymeA towards plasmodia with preliminary results gained. |
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| Keywords: | artemisinin coenxyne A antinalarial mechanism |
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