Reduction of 4-oxo-4,6,7,8(5H)-tetrahydropyrrolo[3,2-c]azepines |
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Authors: | K Dager P B Terent'ev |
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Institution: | (1) M. V. Lomonosov Moscow State University, Moscow |
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Abstract: | 1,2-Diaryl-4,6,7,8(5H)-tetrahydropyrrolo3,2-c]azepines are obtained via the reduction of 1,2-diaryl-4-oxo-4,6,7,8(5H)-tetrahydropyrrolo3,2-c]azepines with lithium aluminum hydride. In the case of a bromophenyl substituent reduction of the bromine atom occurs as well; similarly, in the case of a nitroaryl-substituted lactam, reduction of the amide carbonyl function is accompanied by reduction of the nitro group to an azo group.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 63–65, January, 1985. |
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