| Nuclephilic ring opening of epoxides promoted by multi-site phase-transfer catalyst:An efficient and eco-friendly route to synthesis of β-hydroxythiocyanate |
| |
| 引用本文： | Ali Reza Kiasat,Roya Mirzajani,Haji Shalbaf,Tahereh Tabatabaei. Nuclephilic ring opening of epoxides promoted by multi-site phase-transfer catalyst:An efficient and eco-friendly route to synthesis of β-hydroxythiocyanate[J]. 中国化学快报, 2009, 20(9): 1025-1029. DOI: 10.1016/j.cclet.2009.04.015 |
| |
| 作者姓名： | Ali Reza Kiasat Roya Mirzajani Haji Shalbaf Tahereh Tabatabaei |
| |
| 作者单位： | Chemistry Department,College of Science,Shahid Chamran University,Ahvaz 61357-4-3169,Iran |
| |
| 基金项目： | the partial support of this work by Shahid Chamran Research Council |
| |
| 摘 要： | A highly effective and mild protocol for ring opening of epoxides with NH4SCN in the presence of catalytic amount of a multisite phase-transfer catalyst,α,α′,α″-N-hexakis(triethylammoniummethylene chloride)-melamine,is developed.A variety ofβ-hydroxy thiocyanates as important intermediates in agricultural and pharmaceutical chemistry were obtained in high yields with excellent regioselectivity and in short reaction times.
|
| 关 键 词： | 相转移催化剂 环氧化合物 高效率 路线 环保 开环 亲核 合成 |
| 收稿时间： | 2009-01-04 |
Nuclephilic ring opening of epoxides promoted by multi-site phase-transfer catalyst:An efficient and eco-friendly route to synthesis of β-hydroxythiocyanate |
| |
| Ali Reza Kiasat,Roya Mirzajani,Haji Shalbaf,Tahereh Tabatabaei Chemistry Department,College of Science,Shahid Chamran University,Ahvaz --,Iran. Nuclephilic ring opening of epoxides promoted by multi-site phase-transfer catalyst:An efficient and eco-friendly route to synthesis of β-hydroxythiocyanate[J]. Chinese Chemical Letters, 2009, 20(9): 1025-1029. DOI: 10.1016/j.cclet.2009.04.015 |
| |
| Authors: | Ali Reza Kiasat Roya Mirzajani Haji Shalbaf Tahereh Tabatabaei Chemistry Department College of Science Shahid Chamran University Ahvaz -- Iran |
| |
| Affiliation: | Chemistry Department, College of Science, Shahid Chamran University, Ahvaz 61357-4-3169, Iran |
| |
| Abstract: | A highly effective and mild protocol for ring opening of epoxides with NH4SCN in the presence of catalytic amount of a multi-site phase-transfer catalyst, α,α′,α″-N-hexakis(triethylammoniummethylene chloride)-melamine, is developed. A variety of β-hydroxy thiocyanates as important intermediates in agricultural and pharmaceutical chemistry were obtained in high yields with excellent regioselectivity and in short reaction times. |
| |
| Keywords: | Multi-site phase-transfer catalyst P-Hydroxythiocyanate Thiocyanobydrin Epoxide Ring opening Regioselectivity |
| 本文献已被 CNKI 维普 万方数据 ScienceDirect 等数据库收录！ |
