The First Catalytic Enantioselective Nozaki-Hiyama Reaction |
| |
Authors: | Bandini Cozzi Melchiorre Umani-Ronchi |
| |
Institution: | Dipartimento di Chimica "G. Ciamician", Università di Bologna, Via Selmi 2 I-40126 Bologna (Italy). |
| |
Abstract: | The Nozaki-Hiyama reaction can be performed in an enantioselective catalytic way! The catalytic system utilizes 10 mol % of an inexpensive chiral Cr(salen)] complex. The Cr(salen)]/Mn/Me(3)SiCl system effectively promotes the enantioselective addition of allyl chloride to aliphatic and aromatic aldehydes at room temperature (65-89 % ee, 40-60 % yield). |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|