Three new glycolipids with cytolytic activity from cultured marine dinoflagellate Heterocapsa circularisquama |
| |
Authors: | Hiraga Yoshikazu Shikano Tatsuya Widianti Triana Ohkata Katsuo |
| |
Institution: | Department of Chemistry, Graduate School of Science, Kagamiyama, Higashi-Hiroshima 739-8526, Japan. yhiraga@sci.hiroshima-u.ac.jp |
| |
Abstract: | A monogalactosyl monoacylglycerol 1 and two digalactosyl monoacylglycerols 2 and 3 were isolated from a cultured marine dinoflagellate Heterocapsa circularisquama along with known (2S)-1-O-6,9,12,15-octadecatetraenoyl-3-O-beta-D-galactopyranosyl]-sn-glycerol (4). On the basis of spectral analysis, the glycolipid 1 was characterised as (2S)-1-O-3,6,9,12,15-octadecapentaenoyl-3-O-beta-D-galactopyranosyl]-sn-glycerol. The glycolipids 2 and 3 were characterised as (2S)-1-O-3,6,9,12,15-octadecapentaenoyl-3-O-alpha-D-galactopyranosyl-(1' --> 6')-O-beta-D-galactopyranosyl]-sn-glycerol and (2S)-1-O-6,9,12,15-octadecatetraenoyl-3-O-alpha-D-galactopyranosyl-(1' --> 6')-O-beta-D-galactopyranosyl]-sn-glycerol, respectively. The isolated monoacylglycerols 1-4 showed cytolytic activity towards heart and gill cells of oyster. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|