Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fengling Road, Shanghai 200032, PR China
Abstract:
Certonardosterol D2, a polyhydroxysterol isolated from starfish Certonardoa semiregularis with exceptionally potent antitumor activity, was stereoselectively synthesized from natural rich diosgenin via the protocol of Julia olefination and Evans aldol reaction.