Combined directed ortho-metalation, remote metalation, and Stille cross-coupling strategies. Concise stereoselective synthesis of polysubstituted 9H-fluoren-9-ones |
| |
| Authors: | Anne-Sophie Castanet,Jean-Baptiste Vé ron,Asish De,Jacques Mortier |
| |
| Affiliation: | a Université du Maine and CNRS, Unité de Chimie Organique Moléculaire and Macromoléculaire (UMR 6011), Faculté des Sciences, Avenue Olivier Messiaen, 72085 Le Mans Cedex 9, France
b Indian Association for the Cultivation of Science, 700 032 Jadavpur, Kolkata, India |
| |
| Abstract: | The new sequential stereoselective synthesis of diversely substituted 9H-fluoren-9-ones by ortho-lithiation/Bu3SnCl quench of unprotected benzoic acids followed by Stille cross-coupling reaction and remote metalation is reported. |
| |
| Keywords: | ortho and Remote metalations Stille reaction Benzoic acids |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
