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Tandem annulation strategy for the convergent synthesis of benzonaphthopyranones: total synthesis of chartarin and O-methylhayumicinone
Authors:Sutapa Ray
Affiliation:Department of Chemistry, Indian Institute of Technology, Kharagpur 721 302, India
Abstract:A Hauser-initiated tandem annulation has been developed for the rapid regiospecific synthesis of benzonaphthopyranones via formation of two rings in one-pot operation. This strategy has been generalized with benzonaphthopyranones 26, 29, 32, and 35. It has also been employed in a short synthesis of chartarin (3) and O-methylhayumicinone (67).
Keywords:Hauser annulation   Benzonaphthopyranone   Chartreusin   Chrymutasin   Hayumicin
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