Identification of N,N-dimethyltryptamine and beta-carbolines in psychotropic ayahuasca beverage |
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Authors: | Gambelunghe Cristiana Aroni Kyriaki Rossi Riccardo Moretti Luca Bacci Mauro |
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Institution: | Department of Clinical and Experimental Medicine, Division of Legal and Sports Medicine, University of Perugia, Italy. cristiana.gamelunghe@unipg.it |
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Abstract: | Recently many people have shown great interest in traditional indigenous practices and popular medicine, involving the ingestion of natural psychotropic drugs. We received a request to analyze and determine the nature of a dark green liquid with a dark brown plant sediment, which the police had seized at an airport and inside the home of a person belonging to the 'Santo Daime' religious movement. Gas chromatography/mass spectrometry analysis of the extract identified N,N-dimethyltryptamine, a potent hallucinogen, and the beta-carboline alkaloids harmine and harmaline, revealing monoamine oxidase A-inhibiting properties. These substances are typical components of Ayahuasca, a South American psychotropic beverage obtained by boiling the bark of the liana Banisteriopsis caapi together with the leaves of various admixture plants, principally Psychotria viridis. |
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Keywords: | Ayahuasca N N‐dimethyltryptamine harmine harmaline psychotropic drugs gas chromatography/mass spectrometry |
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