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Oximes and nitriles of cardenolides
Authors:I F Makarevich  M V Mokrouz  L Ya Topchii  I P Kovalev  V E Sokolova  Yu I Gubin  N P Bublik and V A Polyakov
Abstract:The influence of the oximation of cardenolides and the production of 10-cyanocardenolides on their biological activity has been studied. The prefered conformation of strophanthidin 19-aldoxime has been established; it has chelate fragment as the result of the orientation in the same direction of the nitrogen atom of the oxime group and the hydroxy groups at C-3 and C-5.All-Union Scientific-Research Institute of the Chemistry and Technology of Drugs, Khar'kov. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 608–612, September–October, 1983.
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