Desktop near-field thermal-lens microscope for thermo-optical detection in microfluidics |
| |
Authors: | Adelina Smirnova Mikhail A Proskurnin Kazuma Mawatari Takehiko Kitamori |
| |
Institution: | Applied Chemistry Department, The University of Tokyo, Tokyo, Japan. |
| |
Abstract: | A new compact near-field desktop-sized diode laser thermal-lens microscope for analysis in microfluidics was proposed. A novel beam-alignment and detection systems provided high signal stability and, along with reduced number of optical elements rendered the instrument portable. The detection of nonfluorescent model species (Fe(II)-bathophenanthroline chelate) in water showed good linearity in the range of 5 × 10(-9) to 1 × 10(-4) M, and the limit of detection was 3.5 × 10(-9) M, which corresponded to 3.5 × 10(-7) absorbance units and provided a 20-fold enhancement in sensitivity compared with existing schematic. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|