Mending the bones with natural products |
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Authors: | Sethi Gautam Aggarwal Bharat B |
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Institution: | Cytokine Research Laboratory, Department of Experimental Therapeutics, University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Box 143, Houston, TX 77030, USA. |
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Abstract: | In this issue, Qiu and colleagues 1] demonstrate in vitro and in vivo activity of a triterpene glycoside from black cohosh. The isolated compound acts as a suppressor of osteoclastogenesis, targeting specifically RANKL, a member of the TNF superfamily. |
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