Synthesis of 4-Aryl-1,5-benzodiazepine-2-carboxamides |
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| Authors: | Kurdina L. N. Zalesov V. V. Kozlov A. P. |
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| Affiliation: | (1) Narcological Dispensary, Municipal Health Protection Office, Perm, Russia;(2) Perm State University, ul. Bukireva 15, Perm, 614600, Russia;(3) Perm State Academy of Agriculture, Perm, Russia |
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| Abstract: | 4,N-Diaryl-1,5-benzodiazepine-2-carboxamides were synthesized by acid-catalyzed reaction of (Z)-4,N-diaryl-2-hydroxy-4-oxo-2-butenamides with o-phenylenediamine or N,N'-bis(triphenylphosphoranediyl)-o-phenylenediamine. The reaction mechanism is discussed. |
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