Acetogenins from Annonaceae: recent progress in isolation, synthesis and mechanisms of action |
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Authors: | Bermejo Almudena Figadere Bruno Zafra-Polo Maria-Carmen Barrachina Isabel Estornell Ernesto Cortes Diego |
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Affiliation: | Laboratoire de Pharmacognosie, associe au CNRS (BIOCIS), Faculte de Pharmacie, Universite Paris-Sud, 92296, Chatenay-Malabry, France. bruno.figadere@cep.u-psud.fr. |
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Abstract: | The aim of the present review is to summarise the knowledge about newly isolated acetogenins (ACGs) in the last six years. It will also report the total syntheses that have allowed either the confirmation or the revision of some structures, together with the biological activities and mechanism of action of such interesting natural products. In fact, of the 417 isolated compounds reviewed, over 176 have been added during the period from 1998 to 2004. |
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