Cage-like amino alcohols. synthesis, reactions, and application |
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Authors: | L I Kas’yan V A Pal’chikov |
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Institution: | 1. Oles’ Gonchar Dnepropetrovsk National University, pr. Gagarina 72, Dnepropetrovsk, 49625, Ukraine
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Abstract: | The review analyzes methods for the synthesis of amino alcohols containing cage-like norbornene, norbornane, and adamantane fragments. Such reactions of amino alcohols as selective functionalization of hydroxy and amino groups, as well as heterocyclizations with formation of nitrogen- and oxygen-containing heterocycles, are considered. Biological activity of cage-like amino alcohols and their derivatives and their use as ligands in catalytic asymmetric syntheses are discussed. |
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