A novel eco-friendly on-water protocol for the synthesis of 2,2-disubstituted 2,3-dihydro-1H-perimidines |
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| Authors: | Nissy Ann Harry Thomas Shilpa Sankuviruthiyil M. Ujwaldev Gopinathan Anilkumar |
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| Affiliation: | School of Chemical Sciences, Mahatma Gandhi University, Priyadarsini Hills, Kottayam, Kerala, India |
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| Abstract: | An efficient green on-water protocol for the synthesis of 2,2-disubstituted 2,3-dihydro-1H-perimidines is demonstrated. The reaction used safer p-toluenesulfonic acid (PTSA) as a catalyst on water at 80°C, for 2 hours affording a novel method for the synthesis of various disubstituted perimidines in moderate to excellent yields. |
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