Introducing new method for the synthesis of polycyclic compounds containing [1,3]dithiine derivatives,with anticancer and antibacterial activities against common bacterial strains between aquatic and human |
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| Authors: | Mohammadreza Moghaddam-Manesh Sara Hosseinzadegan |
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| Affiliation: | 1. General Bureau of Standard Sistan and Baluchestan Province, Iranian National Standards Organization, Zahedan, Iran;2. Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, Zahedan, Iran |
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| Abstract: | In this study, glycerol:potassium carbonate used as a green deep eutectic solvent, for synthesis of polycyclic compounds containing [1,3]dithiine derivatives. The antimicrobial properties of the derivatives against Lactococcus garvieae and Edwardsiella tarda were tested as bacterial strains between aquatic and human based on the minimum inhibitory concentration (MIC), the minimum lethal concentration (MBC) and inhibition zone diameter (IZD). In addition to antimicrobial properties, cytotoxicity testing was performed against MCF-7 breast cancer cells via MTT cell viability assay. |
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