A new method for the synthesis of 5-amidinobarbiturates |
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Authors: | I V Paramonov N A Belyaev V A Bakulev |
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Institution: | (1) Ural State Technical University, 19 ul. Mira, 620002 Ekaterinburg, Russian Federation |
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Abstract: | The reactions of 5-arylamino(methylthio)methylene]pyrimidine-2,4,6(1H,3H,5H)-triones with different aliphatic and aromatic amines were studied. A series of 5-amidinobarbiturates was synthesized. A
new and preparatively convenient method for their synthesis appropriate for the use in the combinatorial chemistry was developed.
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 8, pp. 1557–1563, August, 2007. |
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Keywords: | barbituric acids thioimidates thioamides amidines |
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