Instability of flat spacetime in semiclassical gravity

The semiclassical theory of gravity is considered in which an asymptotically flat background metric is coupled to quantized matter. We show that, in general, there are modes with spacelike wave vectors for small metric fluctuations around flat spacetime. Besides the usual axioms of quantum field theory in flat spacetime, the proof rests on the existence of a hard trace anomaly in the energy-momentum tensor due to matter self-couplings. Two possible interpretations of the result are discussed.