NHC-catalyzed enantioselective [2 + 2] and [2 + 2 + 2] cycloadditions of ketenes with isothiocyanates |
| |
| Authors: | Wang Xiao-Na Shen Li-Tao Ye Song |
| |
| Institution: | Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. |
| |
| Abstract: | The enantioselective N-heterocyclic carbene-catalyzed formal 2 + 2] and 2 + 2 + 2] cycloaddition of ketenes and isothiocyanates were developed. Reaction with N-aryl isothiocyanates at room temperature favors the 2 + 2] cycloaddition, while reaction with N-benzoyl isothiocyanates at -40 °C favors the 2 + 2 + 2] cycloaddition. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
