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Nucleotide recognition by macrocyclic receptors |
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| Authors: | Andrew D Hamilton Alex Muehldorf Suk-Kyu Chang Nalin Pant Shyamaprosad Goswami Donna van Engen |
| Institution: | (1) Department of Chemistry, Princeton University, 08544 Princeton, NJ, USA;(2) Present address: Chung-Ang University, Seoul, Korea |
| Abstract: | It is shown that complementary positioning of recognition sites (particularly hydrogen bonding, stacking and hydrophobic groups) into a macrocyclic structure can lead to very strong and specific complexation of uncharged organic molecules. |
| Keywords: | Molecular recognition nucleotide thymine guanine barbiturate |
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