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A new type of boronic acid fluorescent reporter compound for sugar recognition |
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| Authors: | Wenqian Yang Binghe Wang |
| Institution: | a Department of Chemistry, North Carolina State University, Raleigh, NC 27695-8204, USA b Department of Chemistry and Center for Biotechnology and Drug Discovery, Georgia State University, Atlanta, GA 30302-4089, USA |
| Abstract: | Fluorescent boronic acids that change fluorescent properties upon carbohydrate binding are very useful for the preparation of fluorescent sensors for sugars. Herein we report 5-quinolineboronic acid (5-QBA) that shows significant fluorescent property changes through a unique pKa-switching mechanism upon binding a diol in aqueous solution. |
| Keywords: | Boronic acid Sensing Sensor Fluorescent Quinoline pKa Sugar recognition Heterocycles |
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