A novel redox-sensitive protecting group for boronic acids, MPMP-diol |
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Authors: | Jun Yan |
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Affiliation: | Department of Chemistry and Center for Biotechnology and Drug Design, Campus Box 4089, Georgia State University, Atlanta, GA 30302-4089, USA |
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Abstract: | A new boronic acid protecting group, 1-(4-methoxyphenyl)-2-methylpropane-1,2-diol (MPMP-diol), has been developed. Both protection and deprotection can be accomplished under mild conditions with quantitative conversions. The deprotection can be carried out using 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ). |
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Keywords: | Boronic acid Protecting group DDQ |
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