Cespitulactams A, B, and C, three new nitrogen-containing diterpenes from Cespitularia taeniata May |
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| Authors: | Ya-Ching Shen Yun-Sheng Lin Yuan-Bin Cheng |
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| Affiliation: | a Department of Marine Biotechnology and Resources, National Sun Yat-Sen University, Kaohsiung 804, Taiwan, ROC
b National Research Institute of Chinese Medicine, Taipei 112, Taiwan, ROC |
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| Abstract: | Three new nitrogen-containing diterpenoids, designated cespitulactams A (1), B (2), and C (3), were isolated from Cespitularia taeniata May. Compounds 1-3 are novel structures having a phenylethyl amino side at C-10 and with an amide function at C-20. Their structures were determined on the basis of extensive spectroscopic analysis and chemical correlation. The cytotoxicity of 1 and its monoacetate (6) were also evaluated against human cancer cell lines. |
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