Selective alkylation of a 6,7-dihydroxyquinazoline |
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| Authors: | Craig S Harris Laurent F Hennequin Olivier A Willerval |
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| Institution: | a AstraZeneca, Centre de Recherches, Z.I. la Pompelle, BP1050, 51689 Reims Cedex 2, France
b AstraZeneca, Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom |
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| Abstract: | A convenient 3-step multi-parallel process for the preparation of 4-(3-chloro-2-fluoroanilino)-6,7-bisalkoxyquinazolines is highlighted. |
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| Keywords: | Selective Mitsunobu Quinazoline |
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