New synthetic route for the enantioselective total synthesis of salinosporamide A and biologically active analogues |
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| Authors: | Reddy Leleti Rajender Fournier Jean-François Reddy B V Subba Corey E J |
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| Affiliation: | Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA. |
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| Abstract: | [reaction: see text] A total synthesis of the salinosporamide analogue 3 is described that starts with the novel cyclization 4 --> 5. |
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