Trace elements in human cancerous and healthy tissues: A comparative study by EDXRF,TXRF, synchrotron radiation and PIXE |
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Authors: | M.L. Carvalho,T. Magalhã es,M. Becker,A. von Bohlen |
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Affiliation: | 1. Faculdade de Ciências, Centro de Física Atómica Universidade de Lisboa, Av. Prof. Gama Pinto 2, 1649-003 Lisboa, Portugal;2. Institute for Analytical Sciences (ISAS), Bunsen-Kirchhoff-Str. 11, 44139 Dortmund, Germany |
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Abstract: | It is known that trace elements play an important role in a number of biological processes. These include the activation or inhibition of enzymatic reactions, competition between elements and metal proteins for binding positions and modifications in the permeability of cellular membranes. These elements may also influence carcinogenic processes, thus the knowledge of trace element concentrations in healthy and neoplastic tissues might help in diagnostic and in the etiology and development of cancer. |
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Keywords: | Human cancerous tissues Total-reflection X-ray fluorescence Energy dispersive X-ray fluorescence Proton-induced X-ray emission Synchrotron radiation |
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