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In vitro Evaluation of Hexagonal Polymeric Micelles in Macrophage Phagocytosis |
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| Authors: | Hsieh‐Chih Tsai Che‐Hau Chang Yie‐Chan Chiu Shuian‐Yin Lin Che‐Ping Lin Ging‐Ho Hsiue |
| Abstract: | This paper develops a non‐spherical polymeric micelle using an amphiphilic block copolymer and a porphyrin crystalline structure. The nanoscale polymer micelles were characterized by transmission electron microscopy (TEM) and atomic force microscopy (AFM), revealing particle sizes of approximately 150 nm with a particular shape in the hexagonal lattice. The shape shows the selective uptake efficacy for the HeLa and macrophage cells, and inhibits phagocytosis against the macrophage.  |
| Keywords: | hexagonal lattice macrophage polymeric micelles tumor targeting |