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I2O5 promoted iodosulfenylation of indoles under metal-free conditions |
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| Authors: | Wangyang Wang Fuyuan Zhu Zhaohua Yan Mingchuang He Sen Lin |
| Institution: | College of Chemistry, Nanchang University, Nanchang 330031, PR China |
| Abstract: | A mild, efficient, and metal-free strategy to construct 2-iodo-3-arylthioindoles was developed via I2O5-promoted iodosulfenylation of indoles utilizing simple, cheap and easily available thiophenols as sulfur sources. It is the first time that the iodothiolation difunctionalization of indoles at C-2 and C-3 positions was accomplished with the formation of 2-iodo-3-arylthioindoles in moderate to good yields. |
| Keywords: | Corresponding authors Difunctionalization 2-Iodo-3-arylthioindoles Diiodine pentoxide Metal-free condition |
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