A novel catalyst-free,eco-friendly,on water protocol for the synthesis of 2,3-dihydro-1H-perimidines |
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| Authors: | Nissy Ann Harry Reeba Mary Cherian S. Radhika Gopinathan Anilkumar |
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| Affiliation: | 1. School of Chemical Sciences, Mahatma Gandhi University, Priyadarsini Hills P O, Kottayam, Kerala 686560, India;2. Advanced Molecular Materials Research Centre (AMMRC) Mahatma Gandhi University, Priyadarsini Hills P O, Kottayam, Kerala 686 560, India |
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| Abstract: | The first greenest methodology for the synthesis of 2,3-dihydro-1H-perimidines on water is described. 1,8-Diamino naphthalene was reacted with different types of aldehydes at room temperature to furnish the product in moderate to excellent yields in 30 min. A multi-gram scale reaction is also performed to ensure the scalability of the reaction. |
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| Keywords: | Corresponding author at: School of Chemical Sciences, Mahatma Gandhi University, Priyadarsini Hills P O, Kottayam, Kerala 686560, India. Heterocycle Perimidine On-water Green reaction |
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