A Novel Approach to Functionalization of Aryl Azides through the Generation and Reaction of Organolithium Species Bearing Masked Azides in Flow Microreactors |
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Authors: | Daisuke Ichinari Yosuke Ashikari Kyoko Mandai Yoko Aizawa Jun‐ichi Yoshida Aiichiro Nagaki |
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Abstract: | A novel straightforward method for aryl azides having functional groups based on generation and reactions of aryllithiums bearing a triazene group from polybromoarenes using flow microreactor systems was achieved. The present approach will serve as a powerful method in organolithium chemistry and open a new possibility in the synthesis of polyfunctional organic azides. |
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Keywords: | azides flow chemistry microreactors organolithium reagents |
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