A carrier-free and recyclable protocol for the cross-coupling of terminal alkynes with arylboronic acids in H2O/TBAB |
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| Authors: | Bo-Xiao Tang Ren-Yun Kuang Ji-Wu Wen Xiang Huang Zhen-Xing Zhang Yu-Jun Shen Jia-Ping Chen Wen-Ying Wu |
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| Institution: | School of Chemistry and Chemical Engineering, The Key Laboratory of Coordination Chemistry of Jiangxi Province, and Institute of Applied Chemistry, Jinggangshan University, Ji’an 343009, China |
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| Abstract: | A new and recyclable protocol was developed for Pd(OAc)2-catalyzed the cross-coupling reaction of terminal alkynes with arylboronic acids using environmentally friendly H2O/TBAB as reaction medium. A series of cross-coupling products containing internal acetylenic bond can be obtained with good selectivity and yield. The Pd(OAc)2/H2O/TBAB system was stable in the Sonogashira-type cross-coupling reaction and could be used at least three cycles without considerable decrease in catalytic performance. The results suggest that the unsupported and recyclable systems can be extended to the other realm of C | |
| Keywords: | Corresponding author Reusability Carrier-free Sonogashira-type coupling |
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