Oplopanphesides A-C, three new phenolic glycosides from the root barks of Oplopanax horridus |
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Authors: | Huang Wei-Hua Zhang Qing-Wen Meng Lan-Zhen Yuan Chun-Su Wang Chong-Zhi Li Shao-Ping |
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Institution: | Institute of Chinese Medical Sciences, University of Macau, China. |
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Abstract: | Three new phenolic glycosides, named oplopanphesides A-C (1-3), have been isolated from the root barks of Oplopanax horridus. Their structures were elucidated by a combination of spectroscopic analyses, including 1D- and 2D-NMR techniques. These phenolic glycosides possess a novel feature in their sugar moieties that a 3-hydroxy-3-methylglutaryl moiety was connected with C-6 of the β-D-glucopyranosyl group. Those compounds showed no cytotoxic effects against human cancer cell lines (MDA-231 and MCF-7) by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) method. |
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