Isoswertisin flavones and other constituents from Peperomia obtusifolia |
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Authors: | Mota Jonas da S Leite Ana C Kato Massuo J Young Maria Claudia M Bolzani Vanderlan da S Furlan Maysa |
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Institution: | Instituto de Quimica, Universidade Estadual Paulista, Araraquara, SP, Brazil. |
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Abstract: | A phytochemical investigation of the leaves and stems of Peperomia obtusifolia (Piperaceae) yielded a new flavone C-diglycoside isoswertisin-4'-methyl-ether-2'α-L-rhamnoside (1), along with four known compounds: isoswertisin-2'α-L-rhamnoside (2), (+)-diayangambin (3), 2-episesalatin (4) and corchoionoside C (5). The structures of the two flavone C-diglycosides (1, 2) were elucidated on the basis of 1D and 2D NMR spectroscopy and MS spectrometric data. These flavones were evaluated by bioautographic assay against Cladosporium cladosporioides and C. sphaerospermum and showed weak antifungal activity. |
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