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Organocatalytic enantioselective Friedel-Crafts reaction of pyrrole derivatives with imines
Authors:Li Guilong  Rowland Gerald B  Rowland Emily B  Antilla Jon C
Affiliation:Department of Chemistry, University of South Florida, 4202 East Fowler Avenue CHE205A, Tampa, Florida 33620, USA.
Abstract:A highly enantioselective Friedel-Crafts reaction of pyrrole derivatives with N-acyl imines catalyzed by chiral phosphoric acids was developed. The reactions produced the pyrrole derivatives in high yields and enantioselectivity.
Keywords:
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