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Synthesis of Ethyl 3-Fluoroalkyl-3-Halo Acrylate With CH_2N_2
摘    要:Thedevelopmentofnewandeffcientsyntheticmethodologiesfortheselectiveintroductionoffluorine-c0ntaininggroupintoorganicmoleculesiscurrentlyofconsiderableinterestbecauseoftheiruniquebiologicalactivitiesinmedicineandagrochemicals.lThoughsomereportsonthesynthesisoffluoroalkylsubstitutedpyrazolesappearedinrecentyears2-synthesisof4-fluoroalkylsubstitutedpyrazolesisquitelimited3.Inacontinuousstudyonthesynthesisoffluorine-containingheterocycles,wefoundethyl3-fluoroalkyl-3-hal0acrylate4couldreactwithCH2…

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