"Click chemistry" inspired synthesis of pseudo-oligosaccharides and amino acid glycoconjugates |
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Authors: | Hotha Srinivas Kashyap Sudhir |
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Institution: | Combi Chem-Bio Resource Center, Division of Organic Chemistry: Synthesis, National Chemical Laboratory, Pune 411 008, India. s.hotha@ncl.res.in |
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Abstract: | reaction: see text] Various pseudo-oligosacchardies and amino acid glycoconjugates were synthesized via an intermolecular 1,3-dipolar cycloaddition ("click") reaction using easily accessible carbohydrate and amino acid derived azides and alkynes as building blocks. It is pertinent to mention that the conjugation reaction is highly regioselective and high yielding and can be carried out under mild reaction conditions. |
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