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Total synthesis of UCS1025A |
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| Authors: | Lambert Tristan H Danishefsky Samuel J |
| Institution: | Laboratory for Bioorganic Chemistry, Sloan-Kettering Institute for Cancer Research, New York, New York 10021, USA. |
| Abstract: | The enantioselective total synthesis of the telomerase inhibitor UCS1025A has been accomplished. The key transformation involves a remarkable boron Reformatsky coupling of iodolactone 13 and aldehyde 17. |
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