Use of chemically-bonded cyclodextrin stationary phase for high performance liquid chromatographic determination of feldene capsules |
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| Authors: | A N Ahmed S M el-Gizawy |
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| Institution: | College of Pharmacy, Department of Pharmaceutical Chemistry, University of Assiut, Egypt. |
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| Abstract: | A novel high performance liquid chromatographic method (HPLC) is presented for the quantitative determination of piroxicam in capsule formulation (Feldene capsule). Samples are separated on a chemically bonded beta-cyclodextrin column (Cyclobond I) with a mobile phase of 75% 0.05M phosphate buffer (pH 7.0) and 25% methanol. The effluent is monitored by a spectrophotometric detector with a 254-nm filter. The method is rapid, accurate, and precise. |
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