Biotransformation of Implanted Coral in Some Animals Studied by Neutron Activation Analysis |
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Authors: | J. L. Irigaray H. Oudadesse T. Sauvage |
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Affiliation: | (1) Laboratoire de Physique Corpusculaire de Clermont-Ferrand, CNRS/IN2P3 - Université Blaise Pascal, 63177 AUBIERE Cedex, France;(2) Laboratoire de Physique Corpusculaire de Clermont-Ferrand, CNRS/IN2P3 - Université Blaise Pascal, 63177 AUBIERE Cedex, France |
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Abstract: | In vivo behavior of biomaterial is dependent on the site of implantation. Characterization by atomic element transfers versus the implantation duration is a quantitative approach to the phenomenon. Here, bioactive coral is implanted in ovine, porcine and rabbit thighbones and not in sheep jawbones as previously reported. Biopsies extracted between 1 and 24 weeks are analysed by fast neutron activation. Mineral composition of the coral is greatly modified: Ca, P, Mg and Sr concentrations become comparable to those of mature bone some months after the implantation. Results suggest a bioactive resorption followed by apatite formation. |
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