New Fluorescent Conjugates of Uridine Nucleoside and Substituted 1,8-Naphthalimide: Synthesis, Weak Interactions and Solvent Effects on Spectra |
| |
| Authors: | Wen Zhang Yanli Wang Yufang Xu Xuhong Qian |
| |
| Affiliation: | (1) Institute of Pesticides and Pharmaceuticals, East China University of Science and Technology, P.O. Box 544, Shanghai 200237, China, CN;(2) State Key Lab. of Fine Chemicals, Dalian University of Technology, P.O. Box 40, 158 Zhongshan Road, Dalian 116012, China, CN;(3) Shanghai Key Lab. of Chemical Biology, Shanghai 200237, China, CN |
| |
| Abstract: | Summary. Novel fluorescent conjugates of uridine nucleoside and 4-dimethylamino-1,8-naphthalimide via linkage with different length, and their precursors were synthesized. Their spectroscopic properties were examined in ten different solvents. It was found that the spectroscopic properties for these conjugates are strongly dependent on polarity and hydrogen bonding ability of solvents. Their fluorescence spectra are also strongly influenced by intramolecular aromatic stacking and hydrogen bonding between the base or sugar moiety of the uridine nucleoside and naphthalimide moiety, which is controlled by the length of the linker. Corresponding author. E-mail: xhqian@dlut.edu.cn; xhqian@ecust.edu.cn Received May 27, 2002; accepted (revised) July 16, 2002 |
| |
| Keywords: | . Fluorescent conjugates Uridine nucleoside Absorption and emission spectra Solvent effects. |
| 本文献已被 SpringerLink 等数据库收录！ |
|
